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A failed laboratory experiment in the Bio-weapons division of the military-industrial complex known as ManCorp, mysteriously transformed mild-mannered lab technician Pete Plus+ into the SHEMALE a hybrid humanoid robot. In an attempt to cover their tracks, ManCorp decided to destroy SHEMALE, so the secrets of their sinister experiments would remain unknown, but SHEMALE escaped, and went into hiding in a subterranean cave system beneath a metropolis in the North-East of England called Newcastle-upon-Tyne.